Michelangelo's paintings on the ceiling of the Sistine Chapel are first shown to the general public. Michelangelo was originally commissioned to paint the ceiling in 1508, and it was only supposed to consist of golden stars in a blue sky.
At this time Michelangelo is better known for his sculpture than for his paintings, and sculpture is definitely his preferred medium. Nevertheless, Pope Julius II insists that he is the best person for this job and encourages him to move forward.
Michelangelo himself had to design and construct the scaffolding that would allow him to reach the high ceiling, and he has had to do all of his work while laying on his back.