Gregory III is elected pope. Born in Syria under the Umayyad Caliphate, he will be the last pope to try and get the Byzantine exarch in Ravenna (political representative of the Byzantine empire in Italy) to confirm his papacy. Pope Gregory III will refuse to support iconoclasm, a movement that's gaining a lot of support in the Byzantine Empire.
This increases the rift between Rome and Constantinople and leads to the Iconoclastic Controversy. Gregory III is the first pope to send emissaries to the Franks and while Charles Martel doesn't respond the later relationship between the Franks and the papacy will be significant for the history of both.