Henry VIII becomes king of England. Henry's desire to produce a male heir and his failure to do so with his first wife, Catherine of Aragon, will lead to a conflict between Henry VIII and the pope — and, after that, the English Reformation.
That King Henry VIII breaks away from the Catholic Church out of personal, selfish reasons rather than ideological or religious conviction can be demonstrated by the fact that, in 1521, he has the writings of Martin Luther publicly burned. He will then later write:
"If Luther will not be converted, let him and his writings be burned together."